Issaqueena Lake sits near the convergence of Little River and Keowee Lake. Flora that you will see on this adventure include cypress, a variety of oak and birch. Wildlife that you may see include Bald Eagles, frogs, alligators, Broad Winged Hawks and falcons. This is a decent fishing lake too, with largemouth, smallmouth and spotted bass as well as crappie, bluegill, yellow perch, catfish, brown trout and rainbow trout.